Articles

Oral Appliance Therapy for Sleep-Disordered Breathing

Joachim Ngiam, Kate Sutherland, Ramesh Balasubramaniam, Marie Marklund, Fernanda Almeida, and Peter Cistulli

Excellent overview chapter in the textbook: Contemporary Oral Medicine (2019) – from several of the world leaders in the field. One of the authors has given permission for use in this program.

Ten Misconceptions That Dentists Have About Treating Obstructive Sleep Apnea

B. Gail Demko, DMD JDSM Vol 5 No3 2018

“This article addresses the ten misconceptions that many dentists have come to believe in the field of dental sleep medicine, and it uses published data to explain that many of these concepts are not supported by science. Evidence-based dental sleep medicine knowledge and protocols are necessary in order to provide optimal patient care, and dentists must understand that dental sleep medicine is an evolving field with a growing body of information that will continue to challenge previously accepted concepts.”

Health Outcomes of Continuous Positive Airway Pressure versus Oral Appliance Treatment for Obstructive Sleep Apnea

Peter Cistulli et al

This is a landmark article comparing CPAP and oral appliances, back to back, establishing oral appliances as a major treatment, even for severe forms of obstructive sleep apnoea.

Management of Side Effects of Oral Appliance Therapy for Sleep-Disordered Breathing

Rose D. Sheats, DMD; Thomas G. Schell, DMD; Alan O. Blanton, DDS; Patricia M. Braga, DDS; B. Gail Demko, DMD; Leslie C. Dort, DDS; Donald Farquhar, DDS; Sheri G. Katz, DDS; Jean-Francois Masse, DMD; Robert R. Rogers, DMD; Steven C. Scherr, DDS; David B. Schwartz, DDS; Jamison Spencer, DMD, MS

This article is a consensus from a group of experienced clinicians on assessing and managing the various side effects encountered with oral appliance therapy.

Update on Oral Appliance Therapy

Marie Marklund, Marc J.A. Braem, Johan Verbraecken

This excellent review article summarises the most recent knowledge about oral appliance therapy treatment, emphasising the factors that predict and contribute to successful outcomes.

Clinical Practice Guidelines for the Treatment of Obstructive Sleep Apnea and Snoring with Oral Appliance Therapy: An Update for 2015

Kannan Ramar, Leslie C. Dort, Sheri G. Katz, Christopher J. Lettieri, Christopher G. Harrod, Sherene M. Thomas, Ronald D. Chervin

This seminal article outlines protocols for the best practice in dental sleep medicine. This is a joint initiative of the American Academy of Sleep Medicine and the American Academy of Dental Sleep Medicine and provides a comprehensive summary of the evidence that has resulted in mandibular advancement splints becoming a key therapy for obstructive sleep apnoea.

Oral Appliance Treatment for Obstructive Sleep Apnea: An Update

Clin Sleep Med. 2014 Feb 15; 10(2): 215–227.

An excellent comprehensive review of dental sleep medicine.

Efficacy of an Adjustable Oral Appliance and Comparison with Continuous Positive Airway Pressure for the Treatment of Obstructive Sleep Apnea Syndrome

Holley, AB et al

A large study of 497 participants comparing the efficacy of oral appliances versus CPAP in the treatment of obstructive sleep apnoea.

Prevalence of Probable Obstructive Sleep Apnea Risk and Severity in a Population of Dental Patients

Levendowski DJ, Morgan T, Montague J, Melzer V, Berka C, Westbrook PR

This article looks at the prevalence of patients with sleep-disordered breathing in dental practice and discusses methods of screening, diagnosing, and managing the many patients identified as having problems.

Effect of a Titration Polysomnogram on Treatment Success with a Mandibular Repositioning Appliance

Fernanda R. Almeida, Jonathan A. Parker, James S. Hodges, Alan A. Lowe, and Kathleen A. Ferguson

This is a landmark study that shows how to improve the results of an oral appliance during a sleep study.

The Incidence and Prevalence of Temporomandibular Disorders and Posterior Open Bite in Patients Receiving Mandibular Advancement Device Therapy for Obstructive Sleep Apnea

Perez CV, de Leeuw R, Okeson JP, Carlson CR, Li HF, Bush HM, Falace DA

This article, from some of the leading researchers and clinicians in the field, discusses the development of temporomandibular symptoms and posterior open bite in patients treated with a mandibular advancement splint.

Objective Measurement of Compliance During Oral Appliance Therapy for Sleep-Disordered Breathing

Dieltjens M, Braem MJ, Vroegop AV, Wouters K, Verbraecken JA, De Backer WA, Van de Heyning PH, Vanderveken OM

This article outlines the use of sensors within oral appliances in order to measure compliance. Objective measurement of usage, rather than relying on self-reports, is crucial for regulatory compliance and increasing the validity of scientific studies.

Referral Patterns and Positive Airway Pressure Adherence upon Diagnosis of Obstructive Sleep Apnea

Jonathon O. Russell, MD, Jordan Gales, Charles Bae, MD, and Alan Kominsky, MD

Large study indicating the poor compliance with CPAP use.

Determinants of Objective Compliance During Oral Appliance Therapy in Patients With Sleep-Disordered Breathing: A Prospective Clinical Trial

Marijke Dieltjens, MBS, PhD; Annelies E. Verbruggen, MD; Marc J. Braem, DDS, PhD; Kristien Wouters, PhD; Johan A. Verbraecken, MD, PhD; Wilfried A. De Backer, MD, PhD; Evert Hamans, MD, PhD; Paul H. Van de Heyning, MD, PhD; Olivier M. Vanderveken, MD, PhD

A study outlining the main factors that lead to non-compliance with a MAS.

Myofunctional Therapy to Treat Obstructive Sleep Apnea: A Systematic Review and Meta-analysis

Macario Camacho, MD, Victor Certal, MD, Jose Abdullatif, MD, Soroush Zaghi, MD, Chad M. Ruoff, MD, RPSGT, Robson Capasso, MD, Clete A. Kushida, MD, PhD

This article is a meta-analysis of published studies looking at the effectiveness of Myotherapy in children and adults.

Oral Appliances for the Management of OSA – An Updated Review of the Literature

Hamoda, M Almeida, F Kohzuka

An excellent overview of all the latest evidence-based understanding on all aspects of oral appliances for sleep apnoea and snoring.

Self-Reported Sleep Quality With Mandibular Advancement Device or Continuous Positive Airway Pressure: A Randomized Clinical Trial on Patients With Mild and Moderate Obstructive Sleep Apnea

Lars Martin Berg, DDS, Torun Karina S. Ankjell, MD, Tordis Agnete Trovik, DDS, MPH, PhD, Anders Sjögren, DDS, PhD, Oddveig G. Rikardsen, MD, PhD, Ketil Moen, DDS, PhD, Yi-Qian Sun, PhD, Vegard Bugten, MD, PhD

This article compares CPAP with Oral appliances in a group of patients with mild to moderate OSA.

Cardiovascular Benefits of Oral Appliance Therapy in Obstructive Sleep Apnea: A Systematic Review

Gilles Van Haesendonck, BSc, Marijke Dieltjens, MBS, Chloé Kastoer, MD, Bharati Shivalkar, MD, PhD, Christiaan Vrints, MD, PhD, Caroline M. Van De Heyning, MD, PhD, Marc J. Braem, DDS, PhD, Olivier M. Vanderveken, MD, PhD

A systematic review of the current evidence regarding the cardiovascular benefits of oral appliance (OA) therapy in obstructive sleep apnea (OSA) patients.

Combination Therapy for Obstructive Sleep Apnea in Order to Achieve Complete Disease Alleviation: From Taboo to New Standard of Care?

Olivier M. Vanderveken, MD, PhD

This article discusses the shift towards combination therapy as a standard for treating obstructive sleep apnea.

The Dentist-Physician Partnership

Kelly A. Carden, MD, MBA

A systematic review of the current evidence regarding the cardiovascular benefits of oral appliance (OA) therapy in obstructive sleep apnea (OSA) patients.

Comparative Effectiveness of the Different Treatment Modalities for Snoring

Stefanie Terryn, MD, Joris De Medts, MD, Kathelijne Delsupehe, MD

This study evaluates the effects of various treatments for snoring and sleepiness, including snoring surgery, mandibular advancement devices (MAD), and continuous positive airway pressure (CPAP).

Long Term Patient Centered Outcomes Following Treatment with Oral Appliance Therapy for Obstructive Sleep Apnea

Carolyn Cronin, DMD, MS, Greg Essick, DDS, PhD, Hunter Boone, BA, Ceib Phillips, PhD, MPH

Study Objectives: This study assessed the long-term general and condition-specific quality of life (QOL) and perceived occlusal and functional changes of individuals with obstructive sleep apnea (OSA) who had oral appliance therapy (OAT) delivery 2 years ago or longer.

The Evolution of Oral Appliance Therapy for Snoring and Sleep Apnea: Where Did We Come From, Where Are We, and Where Are We Going?

B. Gail Demko, DMD

This article explains the innovations of the previous 200 years and how they laid the groundwork for OAT today.

History of Dental Sleep Medicine

Robert R. Rogers, DMD, DABDSM, John Remmers, MD, Alan A. Lowe, DMD, PhD, ABDSM, Peter A. Cistulli, MD, PhD, Jeff Prinsell, DMD, MD, DABDSM, Donald Pantino, DDS, ABDSM

This article highlights the development of Dental Sleep Medicine over the past 25 years.

The Link between Sleep Bruxism, Sleep Disordered Breathing and Temporomandibular Disorders: An Evidence-Based Review

Ramesh Balasubramaniam, BDSc, MS; Gary D. Klasser, DMD; Peter A. Cistulli, MD, PhD; Gilles J. Lavigne, DDS, PhD

This review examines the relationship(s) between sleep bruxism, sleep-disordered breathing, and TMD, providing guidance for clinicians.

Utilization of a Mandibular Advancement Device for Obstructive Sleep Apnea in the Veteran Population

Aaron J. Feinstein, MD, MHS, Michael Zaki, BA, Soroush Zaghi, MD, Tracey Tajima, DDS, Marilene B. Wang, MD

This study examined factors affecting adherence to custom-fit MADs among military veterans with OSA.

Mandibular Advancement Device as a Comparable Treatment to Nasal Continuous Positive Airway Pressure for Positional Obstructive Sleep Apnea

Yoshikazu Takaesu, PhD, Satoru Tsuiki, PhD, Mina Kobayashi, PhD, Yoko Komada, PhD, Hideaki Nakayama, PhD, Yuichi Inoue, PhD

Study Objectives: To evaluate the efficacy of MADs versus nasal CPAP in treating positional OSA.

Maxillomandibular Advancement for Treatment of Obstructive Sleep Apnea: A Meta-Analysis

Soroush Zaghi, MD; Jon-Erik C. Holty, MD, MS; Victor Certal, MD; Jose Abdullatif, MD; Christian Guilleminault, DM, MD, DBiol; Nelson B. Powell, MD, DDS; Robert W. Riley, MD, MS, DDS; Macario Camacho, MD

Maxillomandibular advancement (MMA) is an effective surgical option for OSA that enlarges the upper airway by expanding the skeletal framework.

Influence of Nasal Resistance on Oral Appliance Treatment Outcome in Obstructive Sleep Apnea

Biao Zeng, MD, PhD; Andrew T. Ng, MBBS; Jin Qian, MBiomedEng; Peter Petocz, PhD; M. Ali Darendeliler, PhD; Peter A. Cistulli, MBBS, PhD

This study looked at how nasal resistance impacts MAS treatment outcomes.

Non-CPAP Therapies in Obstructive Sleep Apnoea

W.J. Randerath, J. Verbraecken, S. Andreas, G. Bettega, A. Boudewyns, et al.

Summarises the efficacy of alternative treatment options for OSA.

Orofacial Pain and Sleep

Barry J. Sessle, Kazunori Adachi, Dongyuan Yao, Yoshitaka Suzuki, Gilles J. Lavigne

This chapter provides an overview of orofacial pain mechanisms and their interaction with sleep.

Sleep Bruxism

Ramesh Balasubramaniam, Daniel Paesani, Kiyoshi Koyano, Yoshihiro Tsukiyama, Maria Clotilde Carra, Gilles Lavigne

An excellent review of the diagnosis and management of bruxism.

Prevalence of Probable Obstructive Sleep Apnea Risk and Severity in a Population of Dental Patients

Daniel J. Levendowski, Todd Morgan, Jon Montague, Victoria Melzer, Chris Berka, Philip R. Westbrook

This study assesses the prevalence of OSA in dental patients using a validated questionnaire.

Comparison of Positional Therapy to CPAP in Patients with Positional Obstructive Sleep Apnea

Irene Permut, Montserrat Diaz-Abad, Wissam Chatila, Joseph Crocetti, John P. Gaughan, Gilbert E. D’Alonzo, Samuel L. Krachman

Positional therapy is found to be as effective as CPAP in normalising AHI in positional OSA.

Upper-Airway Collapsibility and Loop Gain Predict the Response to Oral Appliance Therapy in Obstructive Sleep Apnea Patients

Bradley A. Edwards, Christopher Andara, Shane Landry, Scott A.

The study explores how oral appliances impact upper-airway collapsibility, loop gain, and other traits, predicting treatment outcomes.

A Randomized Prospective Long-Term Study of Two Oral Appliances for Sleep Apnea Treatment

AKSSAM GHAZAL, STEFAN SORICHTER, IRMTRUD JONAS, EDMUND C. ROSE

This study compared the long-term effects of two different appliances in treating OSA. 103 patients with OSA were randomised and treated with an IST Herbst or Thornton Anterior Positioner (TAP) appliance.

Temporomandibular Disorder Pain and Dental Treatment of OSA

Dr Robert Merrill

This article discusses the different types of TMD/orofacial pain problems that may occur during the treatment of OSA with a mandibular advancement splint.

Trial Appliances: Are We There Yet?

Marie Marklund, Marc J.A. Braem, Johan Verbraecken

This review article summarises the most recent knowledge about oral appliance therapy treatment, focusing on factors that predict and contribute to successful outcomes.